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Bio-IT-Station


HK Tsai Lab of Bioinformatics

Institute of Information Science, Academia Sinica

News

A Brand New BITS!!

We migrated our website to hugo
May 21, 2020 1 min read

Chinese Year End Party

One-day Taipei Zoo tour and treasure-hunting game. had a very nice meal at Juicy Bun restaurant near NCCU. Wish everyone the best in the future year!
Jan 21, 2020 1 min read

BITS LAB Christmas Party

BITS LAB Christmas Party 2018/12/25 Part 1 : https://youtu.be/bAQyZ2YbxVo Part 2: https://youtu.be/wAJmXS-39P0 Part 3: https://youtu.be/7cqm5itUm4M Part 4: https://youtu.be/iR06qmLz7IM
Dec 30, 2018 1 min read
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Projects

TFAS

A bioinformatics-based exploration on the promoter occupancy and alternative splicing in the human genome

LncRNA

Reveal the function of lncRNA on the transcriptional regulation and epigenetic regulation

Lab Members

Principal Investigator

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Huai-Kuang Tsai

Research Fellow/Professor

Evolutionary Algorithm, Bioinformatics, Regulatory Mechanism, Metagenomics, Computational Biology

Researchers

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Tzuchieh Lin

Research Assistant

Bioinformatics, Genomics, Genetics, Machine Learning

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Yu-Ting Liu

Research Assistant

Computer Vision, Deep Learning, Bioinformatics

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Yen-Ling Liu

Research Assistant

Bioinformatics, NGS Analysis

Grad Students

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Yu-Hsin Chen

Doctoral Student

Bioinformatics, Proteomics

Administration

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Po-Fen Lin

Visiting Scholars

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Jia-Hsin Huang

Assistant Professor

Insect Physiology, Bioinformatics, Genomics

Alumni

See all of the alumnis here

Recent Publications

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H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress.

Transcription-replication conflicts (TRCs) occur when intensive transcriptional activity compromises replication fork stability, …
Shin Yen Chong, Sam Cutler, Jing-Jer Lin, Cheng-Hung Tsai, Huai-Kuang Tsai, Sue Biggins, Toshio Tsukiyama, Yi-Chen Lo, Cheng-Fu Kao
DOI

Inferring the transcriptional regulatory mechanism of signal-dependent gene expression via an integrative computational approach

Eukaryotic transcription factors (TFs) coordinate different upstream signals to regulate the expression of their target genes. To …
Sufeng Chiang, Hisaaki Shinohara, Jia Hsin Huang, Huai Kuang Tsai, Mariko Okada
DOI

Setting boundaries for genome-wide heterochromatic DNA deletions through flanking inverted repeats in Tetrahymena thermophile

Nucleic Acids Research, gkz209, https://doi.org/10.1093/nar/gkz209The Authors wish to correct two errors in Figure 3 part I: The …
Chih-Yi Gabriela Lin, Ju-Lan Chao, Huai-Kuang Tsai, Douglas Chalker, Meng-Chao Yao
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